Calcium assay

Description

Intended Use

For the quantitative in vitro determination of Calcium in serum, plasma and urine. This product is suitable for automated, semi-automated and manual use.

Clinical Significance

Calcium is the most abundant mineral element in the body with about 99% in the bones primarily as hydroxyapatite. The remaining calcium is distributed between the various tissues and extracellular fluids. Calcium is involved in blood coagulation, neuromuscular conduction, excitability of skeletal and cardiac muscle and enzyme activation.

Serum calcium levels are believed to be controlled by parathyroid hormone and vitamin D. An imbalance in any of these modulators can lead to alterations of the body and serum calcium levels. Increases in serum PTH or vitamin D are usually associated with hypercalcemia, which may lead to multiple myeloma and other neoplastic diseases. Hypocalcemia may be observed in hypoparathyroidism, nephrosis and pancreatitis.

Available Applications

• RX misano
• RX monza