Lithium assay

For the quantitative in vitro determination of Lithium in serum. This product is suitable for automated, semi-automated and manual use.

SKU: LM4005 Categories: , , , , , , , Method: Colorimetric Format: Liquid Size: R1 2x18.3ml, R2 2x6.5ml Assay Range: Measuring Range 0.218 to 3.0 mmol/L Working Stability: Unopened reagent is stable up to expiry date when stored at +2 to +8°C, stored protected from sunlight. Available Applications: RX daytona, RX daytona+, RX imola, RX monaco Tags: , , , , , ,

$1,191.47

Out of stock

Description

Intended Use

For the quantitative in vitro determination of Lithium in serum. This product is suitable for automated, semi-automated and manual use.

Clinical Significance

Lithium, administered as Lithium carbonate, is used for the treatment of the manic phase of affective disorders, mania, and manic-depressive illness. It acts by enhancing reuptake of neurotransmitters, thereby reducing their concentration in the neuronal junction. This produces a sedating effect on the central nervous system. It is completely absorbed by the gastro-intestinal tract and peak serum levels occur 2 to 4 hours after an oral dose.

 

The half-life in serum is 48 to 72 hours and is cleared through the kidneys. Reduced renal function can prolong clearance time. Early symptoms of intoxication include apathy, sluggishness, drowsiness, lethargy, speech difficulties, irregular tremors, myoclonic twitching, muscle weakness and ataxia. Levels higher than 1.5 mmol/l (12 hours after a dose) indicate a significant risk of intoxication. Serum lithium concentrations are carried out essentially to ensure compliance and to avoid toxicity.

 

Product Availability

Product Availability

Product availability may vary from country to country.