Description

The 2, 5-dimethoxyamphetamines (2,5-DMA) are a class of designer drugs. They are psychoactive, hallucinogenic stimulants which act as some of the most potent serotonin 5-HT receptor agonists. The psychoactive properties of these drugs are said to range from a stimulant effect at lower doses to hallucinogenic effects at higher doses.

Reported adverse effects include tachycardia, seizures, renal failure and delusional psychosis. A complication associated with 2,5-DMA use is severe vasoconstriction, which can cut off circulation to the limbs and extremities, and in some severe cases lead to amputation. 2,5-DMA drugs are reputedly more potent than traditional amphetamines so there is a higher risk of overdose.