Description

Intended Use

For the quantitative in vitro determination of CK-MB in serum or plasma. This product is suitable for automated, semi-automated and manual use.

Clinical Significance

Creatine Kinase (CK) is internationally accepted as a sensitive and specific indicator of acute myocardial infarction (AMI). There are 3 iso-enzymes of CK, CKMM, CKMB and CKBB. CKBB is produced by the brain in very small insignificant amounts. CKMM is produced by the skeletal and heart tissue and CKMB is produced by the heart muscle. In the vast majority of cases the CK activity rises within 6 hours of an acute infarction. After about 20 hours maximum values are observed. The CK activity generally returns to normal between the fourth and fifth day post- infarction.

Available Applications

• Hitachi 917/Mod P