Aspartate Aminotransferase (AST) assay

For the quantitative in vitro determination of AST in serum or plasma. This product is suitable for automated, semi-automated and manual use.

SKU: AS3876 Categories: , , , , , Method: UV (IFCC) Format: Lyophilised Size: R1a 6x20ml, R1b 6x20ml Assay Range: Measuring range 7.2 to 625 U/l Working Stability: Reconstituted reagent is stable for 14 days at +2 to +8°C or 24 hours at +15 to 25°C Available Applications: Applications are available for a wide range of instruments Tags: , , ,

$189.86

Out of stock

Description

Intended Use

For the quantitative in vitro determination of AST in serum or plasma. This product is suitable for automated, semi-automated and manual use.

Clinical Significance

The aminotransferases are a group of enzymes that catalyse the inter conversions of amino acids and  oxoacids by transfer of amino groups. AST (aspartate aminotransferase or glutamate oxaloacetate transaminase) has been found in the cytoplasm and the mitochondria of cells that have been studied. In cases of mild tissue damage, e.g. liver, the predominant form of serum AST is that from the cytoplasm, with a smaller amount coming from the mitochondria. Severe tissue damage will result in more mitochondrial enzyme being released. Elevated levels of AST can signal myocardial infarction, hepatic disease, muscular dystrophy and organ damage.

 

Although heart muscle is found to have the most activity of the enzyme, significant activity has also been seen in the brain, liver, gastric mucosa, adipose tissue and kidneys of humans.

Product Availability

Product Availability

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